|
| MTA1 |
Myb/SANT; GATA |
No |
Unlikely to be sequence specific TF |
3 Low specificity DNA-binding protein |
No motif |
|
Contains a GATA and SANT domain. Unclear whether the GATA domain is a bona fide DBD as the MTA/RERE family domains are atypical to human GATA domains (see alignment). In CIS-BP there is one protein from C.elegans that shares domain homology and binds a GATA motif (elg-27, ChIP-seq). The GATA ZnF domain of MTA1 is required for its interaction with RBBP4 and RBBP7 (PMID:18067919). Full-length protein has been tried in HT-SELEX and did not yield a motif |
|
| MTA2 |
Myb/SANT; GATA |
No |
Unlikely to be sequence specific TF |
3 Low specificity DNA-binding protein |
No motif |
|
Contains a GATA and SANT domain. Unclear whether the GATA domain is a bona fide DBD as the MTA/RERE family domains are atypical to human GATA domains (see alignment). In CIS-BP there is one protein from C.elegans that shares domain homology and binds a GATA motif (elg-27, ChIP-seq). Full-length protein has been tried in HT-SELEX, and DBD has been tried on PBM - neither yielded motifs |
|
| MTA3 |
Myb/SANT; GATA |
No |
Unlikely to be sequence specific TF |
3 Low specificity DNA-binding protein |
No motif |
|
Contains a GATA and SANT domain. Unclear whether the GATA domain is a bona fide DBD as the MTA/RERE family domains are atypical to human GATA domains (see alignment). In CIS-BP there is one protein from C.elegans that shares domain homology and binds a GATA motif (elg-27, ChIP-seq). Hasnt been tried in any in vitro assays |
|
| RERE |
Myb/SANT; GATA |
No |
Unlikely to be sequence specific TF |
3 Low specificity DNA-binding protein |
No motif |
|
Contains a GATA and SANT domain. Unclear whether the GATA domain is a bona fide DBD as the MTA/RERE family domains are atypical to human GATA domains (see alignment). In CIS-BP there is one protein from C.elegans that shares domain homology and binds a GATA motif (elg-27, ChIP-seq). Has been tried as a DBD in HT-SELEX but did not yield a motif |